2014 · GS Paper 3 · Q11 · 12 marks

Can overuse and free availability of antibiotics without Doctor's prescription, be contributors to the emergence of drug-resistant diseases in India? What are the available mechanisms for monitoring and control? Critically discuss the various issues involved.

In short

Overuse and prescription-free sale of antibiotics are major contributors to drug-resistant disease in India, and the control mechanisms are sound on paper but weakly enforced. Schedule H1 (2014), NAP-AMR (2017) and ICMR's surveillance network exist, yet few inspectors and hospital-only data limit them.

Model answer

Ghissu Editorial · Verified 4 Oct 2026

Introduction
The 2010 NDM-1 superbug, first traced to patients treated in India, made antimicrobial resistance (AMR) a national alarm; bacterial AMR directly caused about 1.27 million deaths worldwide in 2019 (Lancet, 2022).
How Overuse and Over-the-Counter Sale Breed Resistance
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Self-medication

Antibiotics bought over the counter for viral fevers, and courses stopped midway, select the hardiest bacteria.

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Irrational prescribing

A 2022 Lancet Regional Health study found many antibiotic FDCs unapproved by the regulator, and 328 irrational FDCs were banned in 2018.

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Beyond humans

Colistin used as a poultry growth promoter and pharma effluents near Patancheru spread resistance into food and water.

Monitoring and Control Mechanisms and Their Gaps
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Regulation

Schedule H1 (2014) requires chemists to record sales of key antibiotics, but too few drug inspectors enforce it.

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Policy

The Chennai Declaration (2012) and NAP-AMR (2017), now NAP-AMR 2.0 (2025), adopt One Health, yet few states beyond Kerala (KARSAP, 2018) have funded plans.

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Surveillance

ICMR's AMRSN, NCDC's NARS-Net and WHO's GLASS track resistance, mostly in tertiary hospitals, with little animal or environmental data.

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Behaviour change

The Red Line campaign (2016), the 2019 colistin ban and Kerala's Operation AMRITH (2024) help, but informal providers and costly diagnostics sustain blind prescribing.

Conclusion
Overuse and free availability are major drivers of drug-resistant disease in India, and existing mechanisms are sound on paper but weakly enforced. Enforced prescriptions, cheap diagnostics and One Health surveillance, without denying the poor access, will keep antibiotics working.

This model answer is indicative and the model can make mistakes; please verify key facts independently.

Hand-drawn diagram: How misuse breeds resistance. How misuse breeds resistance. Flow: Unprescribed antibiotic → Incomplete or wrong dose → Susceptible bacteria die → Resistant strains survive → Spread via hospitals, sewage
Diagram: How misuse breeds resistance

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Question from the official UPSC Civil Services (Main) Examination 2014 paper. Answer written by Ghissu's engine and checked against our editorial standards. Found an error? Tell us and we correct it within 48 hours.

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