2008 · Paper V · 10 marksFrequently asked

Write about the different types of modern vaccines available today. How are the modern vaccines better than the conventional vaccines ?

In short

Modern vaccines include DNA, mRNA and viral vectored types that give cells genetic instructions to make pathogen proteins, unlike conventional live attenuated or inactivated whole-pathogen vaccines. They are better because they are developed and modified faster, give targeted immunity with fewer side effects and scale up without culturing live pathogens.

Model answer

Ghissu Editorial · Verified 4 Oct 2026

Introduction
The COVID-191 pandemic showcased modern vaccines’ transformative potential, vital for India’s immunisation expansion and disease control, especially in Andhra Pradesh.
Institutional Capacity and Innovation
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Diverse Vaccine Platforms

Modern vaccines (DNA, mRNA, viral vectored) use genetic instructions for immunity, allowing faster modification than conventional vaccines based on whole pathogens.

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India’s Manufacturing Ecosystem

Manufacturers like Serum Institute and Bharat Biotech, along with Zydus Cadila's indigenous DNA vaccine, give India strong capacity that aids distribution in Andhra Pradesh.

Implementation Challenges
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HPV Vaccine Hesitancy2

Gendered mistrust and misinformation cause resistance in rural India, despite government campaigns targeting 11.5 million girls under the Universal Immunisation Programme.

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Infrastructure and Distribution

mRNA vaccines’ cold chain needs complicate deployment in resource-poor areas, unlike conventional vaccines such as Covaxin with simpler storage.

Advantages of Modern Vaccines
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Speed and Adaptability

Rapid development and modification enable responses to variants, unlike slower conventional vaccine production.

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Targeted Immune Response

Genetic vaccines induce strong cellular and humoral immunity, improving protection and reducing side effects.

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Scalability

Platform technologies facilitate mass production without culturing live pathogens, crucial for populous states like Andhra Pradesh.

Way Forward
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Boost Indigenous R&D

Increase funding and infrastructure in Andhra Pradesh to foster innovation and reduce import dependence.

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Strengthen Surveillance

Enhance vaccine safety and disease monitoring systems to ensure efficacy and public trust.

Conclusion
Modern vaccines offer superior tools for India’s health challenges but require overcoming hesitancy and infrastructure issues to fully realise their benefits.

This model answer is indicative and the model can make mistakes; please verify key facts independently.

Hand-drawn diagram: Vaccine Technology Types. Vaccine Technology Types. Diagram (tree): Vaccine Technology Types; Conventional Vaccines; Live Attenuated; Inactivated; Modern Vaccines; DNA and mRNA Vaccines; Viral Vectored Vaccines
Diagram: Vaccine Technology Types

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This chapter in the exam

Human diseases; genetic engineering basics; biotechnology in agriculture; vaccines54 questions

Asked in 8 of 8 sittings since 2008

2008
5
2011
6
2012
15
2016
11
2017
4
2020
5
2023
3
2025
5

Most tested: Vaccines and immunisation, alongside GM crops/biotech agriculture.

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Question from the official APPSC Group-I Mains 2008 paper. Answer written by Ghissu's engine and checked against our editorial standards. Found an error? Tell us and we correct it within 48 hours.

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