2016 · Paper VFrequently asked

What is pharmacogenomics? Discuss the important applications of biotechnology in human health.

In short

Pharmacogenomics studies how a person's genetic makeup shapes their response to drugs, so medicines and doses can be tailored for better efficacy and fewer side effects. Biotechnology also advances health through diagnostics, vaccines like Bharat Biotech's Covaxin, CRISPR gene editing, regenerative medicine and bioinformatics.

Model answer

Ghissu Editorial · Verified 4 Oct 2026

Introduction
Pharmacogenomics integrates genetics and biotechnology to personalize drug therapies, crucial for India’s diverse populations. Telangana’s Genome Valley is a key biotech hub driving this transformation, fostering cutting-edge research and innovation in genomics and precision medicine.
Pharmacogenomics and Its Importance
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Population-Specific Research

India’s multi-ethnic diversity necessitates region-specific studies; programs like the DBT North Eastern Programme1 address this by supporting local genomic research. Telangana’s Genome Valley also exemplifies focused efforts on population-specific pharmacogenomics to optimize drug therapies.

Applications of Biotechnology in Human Health
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Diagnostics and Vaccines

Biotechnology advances diagnostics and vaccine production, exemplified by Bharat Biotech’s Covaxin developed with ICMR, enhancing national health security. These innovations enable early disease detection and targeted treatment.

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Gene Editing and Innovation

Telangana’s Genome Valley leads in gene editing research, supported by initiatives like the Twinning R&D Programme and Visiting Research Professorship (VRP) programme. CRISPR-Cas9 technology is applied to correct genetic disorders and develop novel therapies.

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Capacity Building and Policy

The Biotechnology Labs in Senior Secondary Schools (BLiSS) and BioE3 Policy2 promote education and sustainable biotech growth; Bio-RIDE fosters entrepreneurship. These efforts build a skilled workforce and encourage innovation ecosystems.

Way Forward
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Ethical and Regulatory Strengthening

Clear guidelines on genetic data privacy and equitable access are essential to prevent discrimination and ensure inclusive benefits of biotechnology.

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Public-Private Partnerships

Collaboration among startups, academia, and government can accelerate innovation and commercialization, leveraging Telangana’s biotech ecosystem.

Conclusion
With strategic research, ethical governance, and skill development, India and Telangana can harness pharmacogenomics and biotechnology to improve health outcomes and drive bioeconomy growth, supporting Atmanirbhar Bharat and Sustainable Development Goals.

This model answer is indicative and the model can make mistakes; please verify key facts independently.

Hand-drawn diagram: Biotechnology in Human Health. Biotechnology in Human Health. Diagram (tree): Biotechnology in Human Health; Biotech applications; Diagnostics: genetic screening, markers; Vaccines: Covaxin; Gene editing: CRISPR-Cas9; Bioinformatics: genome data; Pharmacogenomics: drug and dose tailoring
Diagram: Biotechnology in Human Health

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This chapter in the exam

Biotechnology, genetic engineering, stem cells6 questions

Asked in 2 of 2 sittings since 2016

2016
4
2024
2

Most tested: Applied biotechnology in human health and agriculture, especially genetic engineering/biotech applications.

All 6 questions, sorted by sub-topic, with model answers and practice.

Question from the official TGPSC Group-I Mains 2016 paper. Answer written by Ghissu's engine and checked against our editorial standards. Found an error? Tell us and we correct it within 48 hours.

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